Sampling strategies in nested case-control studies.

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Sampling strategies in nested case-control studies.

A stratified version of nested case-control sampling which we call "countermatching" is presented. This design uses data available for all cohort members to obtain a sample for collecting additional information in a case-control substudy. Hitherto the only stratified sampling design for such studies has involved matching of controls to cases with respect to confounding variables. However, in so...

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An incidence density sampling program for nested case-control analyses.

BACKGROUND The nested case-control design can be a very efficient approach to an epidemiological investigation. In order to obtain unbiased estimates of relative risk, controls should be selected by incidence density sampling, which involves matching each case to a sample of those who are at risk at the time of case occurrence. METHODS This paper presents a simple computer program for inciden...

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Reuse of controls in nested case-control studies.

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Nested case-control (NCC) design is a popular sampling method in large epidemiological studies for its cost effectiveness to investigate the temporal relationship of diseases with environmental exposures or biological precursors. Thomas' maximum partial likelihood estimator is commonly used to estimate the regression parameters in Cox's model for NCC data. In this article, we consider a situati...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1994

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.94102s847